PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Tetramer Protein

Description	PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Tetramer Protein (HLU-HP2H5) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M) & VMAPRTVLL peptide (Accession # P13747 (HLA-E*01:03) & P61769-1 (B2M) & VMAPRTVLL). HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Tetramer Protein is assembled by biotinylated monomer (HL0-H82E7) and PE-labeled streptavidin. Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Complex Protein is produced by co-expression of HLA and B2M loaded with CMV UL40 peptide. Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVLL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
Conjugate	PE
Weblink	https://www.acrobiosystems.com/P7316-PE-Labeled-Human-HLA-E%2A01%3A03B2MCMV-UL40-%28VMAPRTVLL%29-Tetramer-Protein.html
Datasheet	https://www.acrobiosystems.com/static/main/products/pdf/ds/HLU-HP2H5.pdf
Transportation	RT
Storage	-20°C