Biotinylated Human Mesothelin / MSLN (296-580) Protein, Fc,Avitag™, premium grade

Description	Biotinylated Human Mesothelin, Fc,Avitag (MSN-H82F6) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Gly 580 (Accession # AAH09272.1). Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro. This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 60.4 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Conjugate	Biotin
Weblink	https://www.acrobiosystems.com/P2568-Biotinylated-Human-Mesothelin--MSLN-%28296-580%29-Protein-FcAvitag%E2%84%A2-premium-grade.html
Datasheet	https://www.acrobiosystems.com/static/main/products/pdf/ds/MSN-H82F6.pdf
Transportation	RT
Storage	-20°C