Anti-Hu CD24 FITC

Exbio | Article no.: 1F-503-T100
PDF Type Clone Specific against Application Host Quantity Price
Primary Antibodies SN3 Human Flow cytometry Murine / Mouse 100 tests 278,– €
Description CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
Clonality SN3
Conjugate FITC
Isotype Antibody IgG1
Storage +4°C


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