Tomivosertib
MedChem Express (MCE)
| Article no.: HY-100022-10mg
| Type | Clone | Specific against | Application | Host | Quantity | Price | |
|---|---|---|---|---|---|---|---|
| Chemicals & Compounds | 10mg | 238,– € |
| Description | Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC50=2-16 nM) in tumor cell lines[1]. Tomivosertib (eFT508) also dramatically downregulates PD-L1 protein abundance[2]. |
|---|---|
| Alternative Names | eFT508 |
| Weblink | https://www.medchemexpress.com/eFT508.html |
| Datasheet | http://file.medchemexpress.com/batch_PDF/HY-100022/Tomivosertib-DataSheet-MedChemExpress.pdf |
| Transportation | RT |
| Storage | -20°C |
| CAS | 1849590-01-7 |
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