SirReal2
MedChem Express (MCE)
| Article no.: HY-100591-10mM*1mL
| Type | Clone | Specific against | Application | Host | Quantity | Price | |
|---|---|---|---|---|---|---|---|
| Chemicals & Compounds | 10mM*1mL | 106,– € |
| Description | SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140 nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1. SirReal2 combined with VS-5584 (HY-16585) suppresses tumor growth and extends the survival rate of mice in tumor xenograft model. SirReal2 is is promising for research of cancer, inflammation and neurodegeneration[1][2][3][4]. |
|---|---|
| Weblink | https://www.medchemexpress.com/sirreal2.html |
| Datasheet | http://file.medchemexpress.com/batch_PDF/HY-100591/SirReal2-DataSheet-MedChemExpress.pdf |
| Transportation | Cool Pack |
| Storage | -20°C |
| CAS | 709002-46-0 |
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