Dehydroepiandrosterone sulfate (Standard)

MedChem Express (MCE) | Article no.: HY-113416R-5mg
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Reference Standards 5mg 284,– €
Description Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality[1][2][3][4].
Alternative Names DHEA sulfate (Standard), Prasterone sulfate (Standard)
Weblink https://www.medchemexpress.com/dehydroepiandrosterone-sulfate-standard.html
Datasheet http://file.medchemexpress.com/batch_PDF/HY-113416R/Dehydroepiandrosterone-sulfate-Standard-DataSheet-MedChemExpress.pdf
Transportation RT
Storage +4°C
CAS 651-48-9


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